Read more at this link about regular checkups when you are using Acnetane/ Orotane/ Roaccutane – wonderful drugs for your skin but can have harmful side-effects that you have to be screened for.
http://www.medscape.com/viewarticle/860133?nlid=102613_430&src=WNL_mdplsfeat_160322_mscpedit_fmed&uac=175274MY&spon=34&impID=1032440&faf=1